Michael Nielsen gave a TEDx talk in Waterloo about Open Science. In 2008 he wrote an influential blog post about the "Future of Science". In this blog post he outlines barriers and is voting for a open market where scientists can outsource scientific problems.
Take a look at the video from the 6th of April 2011:
An older talk from Nielsen introduces his ideas more in detail. Follow the link to the video, in which Michael Nielsen talks about 'Reinventing Discovery' and Open Science at the 2009 .AStronomy conference in Leiden.